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N-Acetyl-L-Cysteine

N-Acetyl-L-Cysteine

Synonyms 1-alpha-Acetamido-beta-mercaptopropionic acid; N-Acetyl-L-cysteine; N-Acetyl-3-Mercaptoalanine; Mercapturic Acid; Mucolyticum; LNAC; NAC

CAS Number: 616-91-1 Molecular Formula: C5H9NO3S Molecular Weight: 163.191 g/mol

Beilstein Registry Number: 1724426 EC Number: 210-498-3 MDL Number: MFCD00004880

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SKU 02194603-CF
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Description

Product Description

N-Acetyl-L-Cysteine

Application Notes

N-Acetyl-L-cysteine acts as a free-radical scavenger and inhibits the production of reactive oxygen species which can damage cellular structures. It is critical for the production of Glutathione, a key antioxidant enzyme in the body. It has also been shown to induce apoptosis in vascular smooth muscle cells, indicating that these cells respond differently to changes in reduction-oxidation state than other tissues that are normally protected by the presence of antioxidants.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Mucolytic agent

Specifications
SKU 02194603-CF
Application Notes N-Acetyl-L-cysteine acts as a free-radical scavenger and inhibits the production of reactive oxygen species which can damage cellular structures. It is critical for the production of Glutathione, a key antioxidant enzyme in the body. It has also been shown to induce apoptosis in vascular smooth muscle cells, indicating that these cells respond differently to changes in reduction-oxidation state than other tissues that are normally protected by the presence of antioxidants.
Beilstein Registry Number 1724426
Biochemical Physiological Actions Antioxidant and mucolytic agent. Increases cellular pools of free radical scavengers. Reported to prevent apoptosis in neuronal cells but induce apoptosis in smooth muscle cells. Inhibits HIV replication. May serve as a substrate for microsomal glutathione transferase.
EC Number 210-498-3
Format Crystalline powder
Grade Cell Culture Reagent
Applications Mucolytic agent
Melting Point 109-110
Moisture Content ≤1.0%
Molecular Formula C5H9NO3S
Molecular Weight 163.191 g/mol
Optical Rotation +21.0 ° to +27.0 ° (c=5, 1M PBS)
Personal Protective Equipment Eyeshields, Gloves, Respirator filter
pH 2 TO 2.75 (1 IN 100 ML)
Physical Appearance White Crystalline Powder
pKa 9.5 (Lit.)
Product Families Description N-Acetyl-L-cysteine
Product Overview N-Acetyl-L-Cysteine
Purity ≥96%
RTECS Number HA1660000
Solubility >24.5 [ug/mL]
Storage and Handling Store at +4 °C.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Vapor Pressure 1.1X10-5 mm Hg at 25 deg C /Estimated/