Doxycycline Hydrochloride

Doxycycline Hydrochloride

Synonyms Biocamycin; Doxigalumicina; Doxycycline hyclate; Doxy-II; Midoxin; Novadox; Retens; Tetradox; Vibradox; Hydramycin; 2-Naphthacenecarboxamide, 4-(dimethylamino)- 1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride

CAS Number: 10592-13-9 Molecular Formula: C22H24N2O8 • HCl Molecular Weight: 480.898 g/mol

Beilstein Registry Number: 5702728 EC Number: 234-198-7 MDL Number: MFCD07357237

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SKU 02195044-CF
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Description

Product Description

Doxycycline Hydrochloride

Application Notes

Doxycycline hyclate is a synthetic oxytetracycline derivative. It has been used to eliminate Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs and to eliminate Ixodes scapularis ticks. It is used to inhibit matrix metalloproteinases and has been used to inhibit the inflammatory response of Lyme Disease.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Antibiotic

Specifications
SKU 02195044-CF
Application Notes Doxycycline hyclate is a synthetic oxytetracycline derivative. It has been used to eliminate Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs and to eliminate Ixodes scapularis ticks. It is used to inhibit matrix metalloproteinases and has been used to inhibit the inflammatory response of Lyme Disease.
Beilstein Registry Number 5702728
Biochemical Physiological Actions Derivative of oxytetracycline. A broad spectrum inhibitor used to inhibit matrix metallo-proteinases (MMP) such as type 1 collagenase in studies on wound healing and tissue remodeling.Doxycycline is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections. It is a Broad spectrum antibiotic and bacteriostatic. Doxycycline shows antiprotozoal properties and is a potent inhibitor of MMPs (matrix metalloproteinases) in vivo. Doxycycline is frequently used to treat Lyme disease, chronic prostatitis, sinusitis, pelvic inflammatory disease acne, rosacea, and rickettsial infections and prophylaxis of anthrax (caused by Bacillus anthracis). It is also effective against Yersinia pestis. Treatment with doxycycline inhibits collagen synthesis.
EC Number 234-198-7
Hazard Statements H302-H315-H319-H335
Applications Antibiotic
Molecular Formula C22H24N2O8 • HCl
Molecular Weight 480.898 g/mol
Personal Protective Equipment dust mask , Eyeshields, Gloves
Physical Appearance Yellow Powder
pKa (10 mg/ml)
Potency 43134
Preparation Method P261-P305 + P351 + P338
Product Families Description Doxycycline
Product Overview Doxycycline Hydrochloride
RTECS Number QI8925000
Source Soluble in water (10 mg/mL - clear; yellowish to yellowish-green solution) and DMSO: soluble (50 mg/mL).
Storage and Handling +4 °C; desiccate; protect from light
Unit Definition It is typically used at a concentration of 20 ug/mL and is stable in media at 37 °C for approximately 5 days.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.